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It is a synthetic substance and is considered to be stimulant and enactogen drug of the amphetamine, phenethylamine and cathinone class.
It consists of the same core amphetamine skeleton whereas it undergoes methyl substitution at R4 position and ethyl group substitution at RN position.
It has been sold in replacement to mephedrone 4-mmc after it was banned. It can be purchased online, as it has become available in It has been found that it is less likely to cause physical addiction, so withdrawal symptoms are not life threatening and minimal in severity.
But consumers have reported psychological addiction to this drug. Bioactivity of 4-MEC It possesses a psychoactive effect. A little have been known about the pharmacological activity of 4 MEC, as the data of human use is not extensively available. The activity of substituted cathinone class of enactogenic and stimulant drugs exerts their action by acting as a dopamine re-uptake inhibitor.
The agonistic effect on this receptor set is responsible for an increased rate of firing of post — synaptic neurons, and triggers both the cognitive and physical stimulation within the individual. Expected Physical effects of 4-methylethcathinone It causes mental and physical stimulation, euphoria, mood lift, empathetic feeling, and increase in sociability, desire to talk with others, relaxed and pleasurable rushing, and increased appreciation of music.
As with other psychoactive drugs, it also causes altered consciousness state, appetite suppression, pupil dilation, unusual body sensations chills, energy, facial flushingchange in body temperature regulation, increase in heart rate and blood pressure, tremor, nystagmus.
There are some reports that indicate its potential of initiating compulsive redosing, sweating, heart palpitations, impaired short term memory, insomnia, trismus tightened jaw muscles and bruxia, muscle twitching, dizziness, light headedness, vertigo.
When it is taken as insufflations, pain and swelling in nose and throat may occur, and can also cause sinusitis, bleeding from nose etc. Dosage Information for 4-methyl-N-ethylcathinone The oral dosage starts from a threshold of 15 — 50 mg.
For mild stimulant effects, the dose can be given from 50 — mg. The commonly used dosage concentration is — mg.
A strong effect is observed on oral administration above — mg dose. In insufflations snortingthe threshold effect is seen with 5 — 25 mg and light effects at 25 — 40 mg dose.
Its common dose ranges from 40 — mg while stronger effect can be obtained at dosage of — mg. This dosage information should not be taken as recommendation. The oral dosage total duration of action is from 2 — 5 hours, with its onset of action starting within 15 — 45 minutes, coming up at 15 — 30 minutes and pleateau at 15 — 30 minutes, and finally coming down at 30 — 90 minutes.
The after effects are from 2 — 4 hours. For insufflations, the total duration of action is from 2 — 3 hours, and onset showing within 5 minutes, coming up at 5 — 10 minutes, pleateau at 10 — 60 minutes and coming down at 45 — 90 minutes.
The after affects are from 2 — 4 hours. Other known names for 4-mec 4-methyl-N-ethylcathinone.Buy Research Chemicals Smokeys Chem Site has been a highly trusted supplier of research chemicals, for many years.
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4-Methylethcathinone or 4-MEC is a chemical that bears a chemical resemblance to caninariojana.com to its similarity to mephedrone, it is thought to be a stimulant and entactogen drug of the phenethylamine, amphetamine, and cathinone chemical classes. 4-MEC is a synthetic stimulant with empathogenic effects that is chemically similar to.